Thermodynamics of Annealing  

  

Aboulela et al. '85

Fareed Aboul-ela, David Koh and Ignacio Tinoco, Jr. "Base-base mismatches. Thermodynamics of double helix formation for dCA3XA3G + dCT3YT3G (X, Y = A,C,G,T)." Nucleic Acids Research 13(13):4811-4824.

An early study which attempted to deduce the enthalpies and entropies of mismatched oligodeoxynucleotide pairs from studies of melting temperatures as determined by absorbance measurements. Unfortunately we discovered that some of the parameters they give are internally inconsistent (containing sign errors) and some are just plain nonsensical (e.g. some implying mismatches that make a strand stronger instead of weaker). We threw out the results from this paper in favor of the results in Werntges et al. '86.

  

Werntges et al. '86

Heinz Werntges, Gerhard Steger, Detlev Riesner and Hans-Joachim Fritz. "Mismatches in DNA double strands: Thermodynamic parameters and their correlation to repair efficiencies." Nucleic Acids Research 14(9):3773-3790, 1986.