Neural Fiber Tracking
Topics
  • Multi-fiber reconstruction from high-angular resolution diffusion imaging using higher-order tensors,
  • spherical de-convolution methods,
  • estimation of tractosemas for fiber tracking using diffusion of asymmetric spherical functions.
  • Collaborators

    Paul R. Carney, MD
    John R. Forder, PhD
    Dena Howland, PhD
    Bing Jian, PhD
    Ritwik Kumar, PhD
    Thomas H. Mareci, PhD
    Baba C. Vemuri, PhD
    Selected Publications

    A. Barmpoutis, B. Jian, B. C. Vemuri, "Adaptive kernels for multi-fiber reconstruction", IPMI, 2009
    A. Barmpoutis, B. C. Vemuri, D. Howland, J. R. Forder, "Regular Positive-Definite Fourth-Order Tensor Field Estimation from DW-MRI", NeuroImage, 2009
    A. Barmpoutis, B. C. Vemuri, D. Howland and J. R. Forder. "Extracting Tractosemas from a displacement probability field for tractography". MICCAI, 2008
    R. Kumar, A. Barmpoutis and B. C. Vemuri. "Multi-fiber reconstruction from DW-MRI using a continuous mixture of von Mises-Fisher distributions". MMBIA, 2008
    A. Barmpoutis, B. C. Vemuri and J. R. Forder. "Fast displacement probability profile approximation from HARDI using 4th-order tensors". ISBI, 2008

    Click here for abstracts, BibTex entries, and PDFs.
    Demo

    This animation shows a real data example from an isolated rat hippocampus. In the beginning of the animation a field of water molecule displacement probability iso-surfaces is shown, estimated using 2nd-order tensorial approximations. One can see that this model fails to parametrize fiber crossings.

    Then, the probabilities corresponding to 4th-order tensorial approximation of the diffusivity are shown. Several fiber crossing profiles are now visible in the spherical function field.

    Finally, the peaks of some spesific probabilities are followed producing fiber tracks with crossings.

    Click here for more experimental results, discussions, plots etc.

    Click here for free software, on-line applets, source code, etc.