Synthetic DW-MRI signal generatorYou can use this applet to generate DW-MRI signal from single fibers or fiber crossings for your own experiments. This method computes an accurate continuous approximation of the DW-MRI signal using adaptive kernels (Fig. 3 from the article: A. Barmpoutis et al. "Adaptive kernels for multi-fiber reconstruction", In the Proceedings of IPMI, 2009). | ||
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InstructionsTechnical details: This method computes an accurate continuous approximation of the DW-MRI signal using adaptive kernels (Fig. 3 from the article: A. Barmpoutis et al. "Adaptive kernels for multi-fiber reconstruction", In the Proceedings of IPMI, 2009). The approximation is based on the simulated DW-MRI signal attenuation from water molecules (using the model by Soderman et al.), whose diffusion is restricted inside a cylindrical fiber of radius rho=5 micrometers and length L=5mm using b-value = 1500s/mm2 and S0=1. This synthetic DW-MRI generator has been used in experiments published in more than 20 journal articles and conference papers, and it has been used for evaluating several multi-fiber reconstruction techniques.Synthetic dataset generation: In order to generate a DW-MRI dataset for your experiments you need first to set the fiber orientations and the number of fibers (1 or 2) using the form in the top of the page and then press enter. The new model will be plotted in 3D on the left. Then the dataset can be generated by defining first a set of unit vectors (magnetic gradient directions) and then press the 'arrow' button. The corresponding signal values will appear in the right text box. Predefined sets of gradient directions: I have constructed various sets of unit vectors that sample uniformly the unit hemisphere and you can use them in order to generate the DW-MRI signal for your exepriments. These sets of vectors were generated by tessallating the icosahedron on the unit hemisphere. Set of 21 directions. Set of 81 directions. Set of 321 directions. System requirements: Please use Internet Explorer (Microsoft) with the latest JAVA platform installed. Disclaimer: You can use this free software for non commercial research purposes and demonstration only without licensing fees and is provided without guarantee or warrantee expressed or implied. This program is NOT in the public domain. For questions please feel free to contact me: Angelos Barmpoutis, abarmpou [at] cise [dot] ufl [dot] edu |